Covid-19 Cepiva

Uporabnik LeQuack je napisal:

Big Pharma mu je najbrž zagrozila.

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Uporabnik AndY1 je napisal:

UK je se vedno del EUja in sicer do konca 2020. Posebno dovoljenje, ki ga ima UK, jim dovoljuje, da to naredijo lahko tudi sami in to so naredili ze zdaj, zato lahko oni zacnejo s cepljenjem naslednji teden.

Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK

The UK is the first country to approve the Pfizer vaccine - with 800,000 doses due to arrive soon.

www.bbc.com

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• če bodo zapleti, bo pozitivno za pokojninsko blagajno
• morebitni zapleti ob rodnosti (glej stran 9) se ne bodo pokazali
• če bo šlo ok, so pa itak zmagali

Uporabnik AndY1 je napisal:

Dr. Wodarg and Dr. Yeadon request a stop of all corona vaccination studies and call for co-signing the petition - 2020 NEWS

On December 1, 2020, the ex-Pfizer head of respiratory research Dr. Michael Yeadon and the lung specialist and former head of the public health department Dr. Wolfgang Wodarg filed an application with the EMA, the European Medicine Agency responsible for EU-wide drug approval, for the immediate...

2020news.de

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This is a strange one with an unknown origin story. Basically, the claim is that there is a protein subunit on the S-protein that is "homologous" to the syncytin-1 protein that facilitates the development of the placenta. Hypothetically, if the syncytin-1 and SARS-CoV-2 spike proteins were similar or exactly alike, there could be some cross-reactivity of antibodies between the S-protein and the syncytin-1 protein.


This is one of those types of myths that has a tiny plausibility in biology, but in reality, it has zero meaning.


Syncytin-1 is an endogenous retroviral element that is the remnant of a 25 million year ago retroviral infection integrated into old-world primates, including humans. In other words, it was incorporated into our genome as a result of retrovirus infection. As I wrote above, retroviruses can change our DNA.


In case you don't know, the evolution of all organisms includes the incorporation of viral DNA into our genome. Occasionally, these viral genes confer some increased fitness, as in the case of syncytin-1 it becomes a part of placental development. About 8% of the human DNA comes from viruses during our long evolutionary past.


This is where it gets somewhat complicated. Even though coronaviruses are not retroviruses, viruses frequently share similar peptides (which are much smaller than proteins, only containing between 2 and 50 amino acids). There is one small peptide within the syncytin-1 protein that is homologous to one small peptide in the S-protein.


This peptide is called "CP-1", and it contains about 3 amino acids. Syncytin-1 has 538 amino acids. The S-protein contains 510 amino acids. In other words, the CP-1 peptide is a tiny part of the structure of each of those proteins.


The immune system generally doesn't recognize small peptides as antigens, because they are so small and because they are so similar to other peptides. An example of this is insulin – it is a small peptide that is found in almost all animals from crabs to humans. Before we made human insulin, we treated type 1 diabetes with porcine and bovine insulin, and the immune system just thought it was human insulin, despite the differences in the peptides.


But there are three critical points that should be emphasized:

1. There is simply no published evidence (as far as I could find) that there is some immune cross-reactivity between the S-protein and syncytin-1. Not only is there no evidence, but it's also not plausible that one small 3-peptide part of those two proteins would induce some sort of cross-reactivity.
2. Women have contracted COVID-19, and there aren't a ton of reports of sudden infertility risks. Remember, the S-protein that is being produced by the mRNA vaccines is the same S-protein in the SARS-CoV-2 virus. If this hypothesis being pushed by anti-vaxxers were true, then it would also be true with "natural" infection.
3. If I'm totally wrong, and there is some weird cross-reactivity between 3 amino acid peptides, then there's more reason to get the vaccine to prevent an infection.

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Pušenjaka smo prosili za komentar in pojasnil nam je, da se je v svojem odgovoru na Facebooku navezal na sterilnost, ki ko omenja intervjuvanec in ki je "dejansko nekaj drugega kot je sterilnost, ki je omenjena v tekstih pod intervjuji in intervju niti ne omenja beljakovine syncytina-1, le kontekst je povezan. Povezava pa je v bistvu spet ponesrečena. Iskreno v svojem odgovoru nenamenoma intervjuvancu v usta polagam nekaj, česar ni izrekel. Priznam, ampak sem spregledal. Intervjuvanec s sterilnostjo misli na "sterilizrajočo imunost", ki je poseben pojem mere za uspešnost cepiva(v pozitivnem smislu), teksti v linkih pod intervjujem pa govorijo o neplodnosti v zvezi z navzkrižno imunostjo med površinskim antigenom na Sars-cov-2 in syncytinom-1 (hud in daljnosežen stranski učinek)." Pušenjak nadalje izpostavi, da je bil njegov namen le opozoriti na pomembnost ustreznega in tudi časovno zadostnega testiranja cepiva, preden se ga dovoli uporabiti na človeštvu.

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Uporabnik AndY1 je napisal:

A tako kot Fafangel pred nedavnim?

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Uporabnik KillaKHAN je napisal:

Definitivno ne tako kot ti. Kadarkoli.

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Uporabnik AndY1 je napisal:

Dr. Wodarg and Dr. Yeadon request a stop of all corona vaccination studies and call for co-signing the petition - 2020 NEWS

On December 1, 2020, the ex-Pfizer head of respiratory research Dr. Michael Yeadon and the lung specialist and former head of the public health department Dr. Wolfgang Wodarg filed an application with the EMA, the European Medicine Agency responsible for EU-wide drug approval, for the immediate...

2020news.de

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Povejmo še, da dr. Yeadon pri Pfizerju ne dela že 9 let (in torej cepiva konkretno ni ne ustvarjal ne sodeloval pri tem). In pa, da je isti dr. Yeadon oktobra trdil, da v UK cepljenje ni potrebno, ker da je epidemije dejansko konec
https://www.politifact.com/factchec...-pfizer-employee-wrong-coronavirus-pandemic-/

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