Bi se ti lahko odrekel hudiča?me ne maraš? by brane_new
ferdi, ti s' moj nrbol prjatau. by Tri Vile.
The greatest trick the devil ever pulled was convincing the world he didn't exist. by Kevin Spacey (The Usual Suspects):
Kako se oklepaš vsake novice...
THE GAMALEYA CENTER STATEMENT
A comprehensive analysis of adverse events during clinical trials and over the course of mass vaccinations with the Sputnik V vaccine showed that there were no cases of cerebral venous sinus thrombosis (CVST).
All vaccines based on adenoviral vector platform are different and not directly comparable. In particular, AstraZeneca’s ChAdOx1-S vaccine uses chimpanzee adenovirus to deliver the antigen, consisting of S-protein combined with leader sequence of tissue-type plasminogen activator. The vaccine from Johnson&Johnson uses human adenovirus serotype Ad26 and full-length S-protein stabilized by mutations. In addition, it is produced using the PER.C6 cell line (embryonic retinal cells), which is not widely represented among other registered products.
Sputnik V is a two-component vaccine in which adenovirus serotypes 5 and 26 are used. A fragment of tissue-type plasminogen activator is not used, and the antigen insert is an unmodified full-length S-protein. Sputnik V vaccine is produced with the HEK293 cell line, which has long been safely used for the production of biotechnological products.
Thus, all of the above vaccines based on adenoviral vectors have significant differences in their structure and production technology. Therefore, there is no reason and no justification to extrapolate safety data from one vaccine to safety data from other vaccines.
The quality and safety of Sputnik V are, among other things, assured by the fact that, unlike other vaccines, it uses a 4-stage purification technology that includes two stages of chromatography and two stages of tangential flow filtration. This purification technology helps to obtain a highly purified product that goes through mandatory control including the analysis of free DNA presence. In addition, the volume of nucleic acid is several dozen times lower in adenoviral vectors compared to Pfizer and Moderna vaccines (1 to 2 mcg vs 50 to 100 mcg, correspondingly).
A study published in The New England Journal of Medicine on April 9, 2021, discusses that the cause of the thrombosis in some patients vaccinated with other vaccines could be insufficient purification that leads to the emergence of significant quantities of free DNA. Insufficient purification or use of very high doses of target DNA/RNA can result in adverse interaction of a patient’s antibodies that activate thrombocytes with elements of the vaccine itself and/or free DNA/RNA, which can form a complex with the PF4 factor.
Link to the study:
https://www.nejm.org/doi/full/10.1056/NEJMoa2104840?query=featured_home
The Gamaleya Center is ready to share its purification technology with other vaccine producers in order to help them minimize the risk of adverse effects during vaccination.
Torej obriši se že enkrat tisto mleko izpod nosu.Bi se ti lahko odrekel hudiča?
Kdo bi ti potem kuhal, pral, pospravljal, peglal....?
Russia Blasts U.S. for Pressing Brazil to Reject Its Vaccine
Russia condemned the U.S. for applying diplomatic pressure on Brazil to reject its Sputnik V Covid-19 vaccine, adding that attempts at political meddling in inoculation campaigns were costing lives.www.bloomberg.com
Toliko o 'teorijah zarote'.
Dol jim vusi za zivljenja. Sputniku in Ivermectinu ne sme uspeti.
To pomeni, da se bomo mask lahko rešili relativno hitro če bo precepljenost dovolj visoka.
Mogoče lahko še pokomentiraš izjavo Gamaleye glede strdkov kot posledice cepiv?Anvisa (brazilska agencija) je objavila da, da so v vsakem lotu, ki so ga testirali (Ad5 lot, A549 celična linija), našli tudi virus, ki se je bil spospoben razmnoževat (naj ne bi bila težava v samem dizajnu, ampak problem s proizvodnjo).
Youtube posnetek zasedanja agencije (slide ob 21:28) (sicer je posnetek dolg 5 ur, tako da AndY1 razumemo, da bo malo trajalo, da boš strokovno raztrgal nekompetetneže pri Anvisi).
Meni so sicer geopolitične zadeve irelevantne, tako da bom povsem neobremenjeno oprazoval diskusijo - ki se je v USA zelo razplamtela.
Je pa res, da so dali pri Anvisi konkretne očitke ven, ki so preverljivi.
Povsem drugče, kot če bi bil komentar da, da je bil design študije 3. faze neoptimalen in da so zaključki statistično nezanesljivi (nič ne povejo, kaj je diretno narobe, samo podatkov ne sprejmejo in moraš narediti novo študijo - tukaj se pravzaprav zatika AZ pri FDA - (če so twitter povzetki, ki sem jiz zasledil korektni)).
Mogoče lahko še pokomentiraš izjavo Gamaleye glede strdkov kot posledice cepiv?
The Gamaleya Center statement
The Gamaleya Center statement | Official website vaccine against coronavirus Sputnik V.sputnikvaccine.com
Oni namreč trdijo, da so strdki posledica nečistosti cepiv - vsaj jaz sem tako razumel.
Kot sem rekel, s Covid pasosem bomo hodili naokoli kot s potnim listom za psa, kjer so notri nalepke za cepljenje proti steklini in je treba cepljenje obnavljati vsake nekaj casa.Po cepljenju obnovitveni odmerek na približno leto in pol
Premalo se spoznam na DNA in PF4 aktivacijo . Bom spremljal ali bo kdo bolj kompetenten povedal kaj o tem.
Je pas šla zadeva precej mimo, ker je Gamaleya trenutno zelo na udaru glede njihovega uradnega twitterja, so branili Sputnik V na precej "dvomljiv" način, vljudni gospodje so uporabili besede bullshit in disgrace glede njihovih objav. Sama Katalin Karikó je komentirala, da so objave zelo vprašljive.
Primerjali so neprimerljivo. In ljudje, ki se spoznajo na to temo, so v trenutku znoreli ali pa izgubili sapo, kako se lahko nekdo spusti tako nizko.
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Karikó Katalin szerint így félrevezető a kormány táblázata a vakcinák hatékonyságáról, ezért itt-ott kiegészítette
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