Covid-19 Zdravila

AndY1

Guru
Osebje foruma
18. sep 2007
22.031
4.047
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Remdesivir claimed the top spot for hospital drug spending in 2021, with sales earning Gilead $4.2 billion in the first nine months alone. The problem is that, at best, the drug doesn’t work.

Despite some initial indication that Remdesivir might slightly reduce recovery time, the World Health Organization conducted a large-scale analysis that found it “had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.” Unsurprisingly, the WHO recommended against using this drug to treat Covid-19 in November 2020 (and still does).

At worst, however, Remdesivir is harmful. A subsequent analysis of the agency’s safety database found it likely caused kidney failure, and when independent trials (those not sponsored by a pharmaceutical company) are analyzed alone, there is a clear statistical trend to harm. WHO also warns that the drug may be associated with an increased reporting of liver problems.
 
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javr

Guru
6. dec 2011
1.599
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Eksperimentalno zdravilo, ki je ta čas še v fazi kliničnega preizkušanja, zbuja upanje za učinkovitejšo terapijo bolnikov z najhujšim potekom covida-19. Imenuje se sabizabulin, razvilo ga je ameriško farmacevtsko podjetje Veru. Začetne ugotovitve tretje klinične faze študije, v kateri je sodelovalo 150 bolnikov na klinikah v ZDA, Braziliji, Argentini, Mehiki, Kolumbiji in Bolgariji, so bile tako spodbudne, da so jo po nasvetu neodvisnega nadzornega odbora predčasno ustavili.
 
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AndY1

Guru
Osebje foruma
18. sep 2007
22.031
4.047
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Pfizer trial of Paxlovid stopped due to lack of efficacy in standard risk patients.
 

Ytbnd

Guru
2. mar 2010
16.149
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Paxlovid


COVID reinfection rate with treatment Biden is taking is more than 40% - and not 2% as marketed: Paxlovid is thought to suppress immune response meaning body can't fight off new infection
 
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